BAYER ASPIRINE 81MG SAFETY COATED: 1X DAILY (REDUCED CHANCE OF HEART INFERENCE?)
120 ENTERIC COATED TABLETS
One pill every day
A child's aspirin every day and you would considerably reduce the risk of a heart attack and cancer. Are we dealing with a miracle pill here, yes or no?
Yes, aspirin is blood thinning
Acetylsalicylic acid, the chemical name of aspirin, is not only an analgesic and anti-inflammatory, but also a blood thinning agent. That is why it is often used for cardiovascular problems. Sjors Konijn, general practitioner in Purmerend, explains: 'The idea is that by diluting blood you are less likely to suffer from the formation of blood clots that could cause a heart attack or stroke.'
Yes, low-dose aspirin is effective as a blood thinner
There are other blood thinners on the market, such as acenocoumarol. That has a slightly stronger effect, but if you take those pills, you have to go to the thrombosis service every two to three weeks to check your blood and adjust the dose if necessary. Clopidogrel is an alternative, but it is very expensive and much less research has been done into its effect. Aspirin has been proven to work in a low (child) dose: 80 mg per day is enough.
Yes, aspirin reduces the risk of cardiovascular disease
General practitioners recommend such a daily aspirin regularly. Sjors Rabbit: 'Swallowing an aspirin in a low dose every day is useful if you already have a history of cardiovascular disease: think of a TIA, myocardial infarction or angina pectoris. Another example: intermittent claudication, also known as display legs, where leg arteries clog. In all these cases, the vessels are affected by calcification or fatty processes. A blood clot can then cut things off immediately and in the worst case result in a new infarction or stroke. Aspirin helps to reduce that chance.'
No, aspirin does have side effects
Sounds like everyone should be on aspirin beforehand. Yet that is not true. This has to do with the possible side effects: stomach pain and even a stomach or brain haemorrhage. The balance is positive for cardiovascular disease sufferers. By taking aspirin preventively, the chance of a new infarction is reduced by about a quarter. In other words: if 1000 patients take aspirin for 2 years, between 35 and 40 infarctions will be prevented, but approximately 1 brain haemorrhage or 8 gastric/intestinal haemorrhages will occur. However, if you are healthy, the benefits of aspirin are smaller. A matter of risk management: the chance that you will then have a stomach or brain haemorrhage outweighs the benefits that aspirin provides for the heart and vessels.
No, the effect of aspirin against cancer is not established
What about all those studies that you see almost weekly with reports that a simple aspirin would work against, for example, colon or prostate cancer and diabetes? Apart from the fact that it is not wise to just go on aspirin because of the possible serious side effects, there is no definitive proof yet. Many of the studies are shaky because, for example, there were too few test subjects or insanely high – and therefore risky – doses were used. Conclusion, standard to the aspirin is not recommended. Even if cardiovascular disease runs in the family, that is no reason to reach for the aspirin in advance. Are you healthy and do you want to reduce your chances of having an infarction or stroke? Then there is only one thing to do: eat healthy and exercise a lot.
Aspirin in the evening more effective blood thinner
Nov 13, 2014• PRESS RELEASE
If you take aspirin daily to prevent cardiovascular disease, it is best to do so in the evening. Aspirin then has more effect, without causing more side effects. That is the most important conclusion from Tobias Bonten's doctoral research. He obtained his doctorate on November 13 for his thesis Time for Aspirin.
If you take aspirin daily to prevent cardiovascular disease, it is best to do so in the evening. Aspirin then has more effect, without causing more side effects. That is the most important conclusion from Tobias Bonten's doctoral research. He obtained his PhD on 13 November for his dissertation Time for Aspirin.
Tens of millions of aspirin tablets are taken every day, not to fight pain, but to keep cardiovascular disease at bay. It is known that most heart attacks occur in the morning. “We therefore thought that aspirin might work better if taken in the evening,” says Tobias Bonten.
Chance of blood clots
The PhD student tested the hypothesis by having three hundred daily aspirin swallowers take the pill in the morning and one group in the evening. Later, he reversed the two groups. Bonten: “We saw that when people take the pill in the evening, their blood is thinner in the morning. The platelets are then less active and the risk of blood clots is smaller.”
In someone with an average day-night rhythm, the platelets become active very early in the morning, during sleep. If you then take your aspirin for breakfast at nine o'clock, you are too late to reduce the daily peak in blood vessel activity - and therefore the risk of blood clots.
Number of heart attacks
About 70 percent of daily aspirin users now take the pill in the morning. So it would be better to do that in the evening, before going to sleep. “Some people think it's bad on an empty stomach, but we didn't see any difference in side effects between the group taking the pill in the morning and the group taking the pill in the evening. My grandmother also takes aspirin every day and has now started taking it at night on my advice.” Bonten emphasizes that only the activity of the platelets has been examined. “I have not investigated whether taking aspirin in the evening actually reduces the number of heart attacks. That is the next step.”
Effect on blood pressure
The PhD student also investigated whether the time of taking aspirin has an effect on blood pressure. “It is known that blood pressure drops in healthy young people when they take aspirin in the evening instead of in the morning. Unfortunately, this turned out not to be the case for patients. Aspirin may be able to lower blood pressure by widening the vessels. But in people who already have cardiovascular disease, the blood vessels are often calcified and therefore probably too stiff to respond well to the blood pressure-lowering effect of aspirin.”
Bonten already presented part of his research at a conference of the American Heart Association last year, and was world news for a while. “The news about the timing of taking aspirin was picked up by the American press and then by a lot of media. For example, it was on the front page of the Telegraaf, and I gave an interview for the BBC and the New York Times," said Tobias Bonten, who is now training to become a general practitioner.
Aspirin has pros and cons
Taking aspirin daily is not recommended for everyone, because it also has side effects. Only in people who have already had a heart attack or stroke do the advantages of blood thinning clearly outweigh the disadvantages. The main side effects of aspirin are stomach irritation and (brain) bleeding. Always consult your doctor before you start taking aspirin.
Tobias Bonten (30) obtained his PhD on 13 November on his thesis Time for Aspirin with Prof. Anske van der Bom and Prof. Frits Rosendaal. His research was made possible in part by a financial contribution from the Heart Foundation.
Much of the aspirin sold in the United States is enteric-coated. Sometimes referred to as a safety coating, these slippery pills are designed to resist stomach acid and pass through the stomach before completely dissolving in the small intestine (enteric comes from the Greek word for gut).
NONE OF THE ABOVE IS INTENDED AS MEDICAL ADVICE. USE IS AT YOUR OWN RISK. CONSULT A DOCTOR IF IN DOUBT AND/OR IF YES ARE ALREADY TAKING OTHER MEDICINES/MEDICINES.